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LasDB: A collective database for laboratory animal strain resources.

Kong Q1,2,3,4, Qin C1,2,3,4.

Author information

1
Institute of Laboratory Animal Science Chinese Academy of Medical Sciences (CAMS) and Comparative Medicine Center Peking Union Medical College (PUMC) Beijing China.
2
NHC Key Laboratory of Human Disease Comparative Medicine Key Laboratory of Human Diseases Animal Model State Administration of Traditional Chinese Medicine Beijing China.
3
Beijing Key Laboratory for Animal Models of Emerging and Reemerging Infectious Diseases Beijing China.
4
Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases Beijing China.

Abstract

BACKGROUND:

With the aim of establishing the most comprehensive database of laboratory animal strains, the "laboratory animal strain resources database" (LasDB) was constructed as a searchable online database of all laboratory animal strains, stocks and mutant embryonic stem-cell lines available worldwide, including inbred, outbred, mutant and genetically engineered strains.

METHODS:

MySQL database software was used to construct the LasDB, offering an easy-to-use interface.

RESULTS:

To date, LasDB has a collection covering data for 21 596 mouse strains, 2062 rat strains, 13 monkey strains, 2 hamster strains, 5 dog strains, 5 rabbit strains and more than 50 other laboratory animal strains. LasDB will be continually improved with regular updates of new laboratory animal strains from all over the world.

CONCLUSION:

To the best of our knowledge, this is the first database that attempts to systematically integrate all available laboratory animal strain data with the aim of supporting open usage and full resource sharing.

KEYWORDS:

comparative medicine; database; laboratory animal; resource; strain


原文链接:https://www.ncbi.nlm.nih.gov/pubmed/30891576